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2017 Core Coins Program


High-throughput sequencing makes it possible to unlock the molecular and genetic bases of diseases, but analyzing the large sequence data sets requires computational resources and expertise that may not be available to all investigators. In response to the growing demand for sequence analysis, the School of Medicine is offering Core ‘coins’ awards through the Computational Biology Consulting Core (CBCC). The awards will provide scientists with leading-edge bioinformatics analysis of RNA sequencing (RNA-seq) or 16S rRNA metagenomics data sets, to be performed at the CBCC. Each award will cover or help defray the cost of analyses, up to a maximum of $5,000. Any additional analysis costs will be the responsibility of the investigator (estimated project costs by data set size are diagramed below). Applications are due by September 30, 2017, and successful proposals will be announced by October 15, 2017.

Applications must be very brief, consisting of: i) a one-page project description, ii) a brief justification for the scope and need for the project and/or how the project responds to this RFA, and iii) the number of, and a brief description of the data sets. Priority will be given to proposals from junior investigators, pilot projects to provide support for grant applications, and analyses of new data, and will be based on agreement from investigators to recognize the Core ‘coins’ program and the CBCC in publications generated as a result of this funding. All data for analyses must be available by the end of the FY2018. Please submit your proposal through the CBCC iLab portal or email it to Liliana Florea (florea@jhu.edu), Associate Professor, Faculty Manager, Computational Biology Consulting Core.

Estimated costs by size of data set.

RNA-seq samples Price estimate Price per sample
(40-100 M reads/sample) ($) ($)



2 1,450 725
3 1,850 617
4 2,300 575
5 2,750 550
6 3,150 525
7 3,575 510
8 4,050 506
9 4,475 497
10 4,950 495
20 8,800 440
40 15,525 388
60 20,700 345
80 24,400 305
100 27,300 273
150 34,500 230
200 40,000 200
>200 Var. 200
Prices for experiments with <40 million or >100 million reads will vary.


16S rRNA samples Estimated price ($) Price per sample ($)



<20 2,000 Var.
40 3,500 88
60 5,000 83
80 6,500 81
100 8,000 80
150 11,000 73
200 14,000 70
250 16,500 66
300 19,000 63
350 21,500 61