Steven L. Salzberg, Ph.D.
  Bloomberg Distinguished Professor of Biomedical Engineering, Computer Science, and Biostatistics
  Director, Center for Computational Biology
  McKusick-Nathans Institute of Genetic Medicine
  Johns Hopkins University
  Mailing address:   Welch Medical Library, Rm 107, 1900 E. Monument St., Baltimore, MD 21205

  Phone: 410-614-6112  Email:
  Lab page:
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Steven Salzberg is the Bloomberg Distinguished Professor of Biomedical Engineering, Computer Science, and Biostatistics and the Director of the Center for Computational Biology in the McKusick-Nathans Institute of Genetic Medicine at Johns Hopkins University. From 2005-2011, he was the Director of the Center for Bioinformatics and Computational Biology (CBCB) and the Horvitz Professor of Computer Science at the University of Maryland, College Park. From 1997-2005 he was Senior Director of Bioinformatics at The Institute for Genomic Research (TIGR) in Rockville, Maryland, one of the world's leading DNA sequencing centers at the time.

Dr. Salzberg received his B.A. degree in English and M.S. and M.Phil. degrees in Computer Science from Yale University, and his Ph.D. in Computer Science from Harvard University.  He joined the Computer Science Department at Johns Hopkins as an Assistant Professor in 1989.

Before switching to bioinformatics and genomics, Dr. Salzberg's research focused on machine learning and its applications to fields ranging from astronomy to molecular biology.  His interest in the human genome project motivated him to develop one of the first computational gene-finding systems for the human genome in the early 1990s.  His initial collaborations with TIGR at that time led to the development of the Glimmer gene finder, which has been used in the analysis of thousands of bacterial, archaeal, and viral genomes, including Borrelia burgdorferi (the Lyme disease bacterium), Treponema pallidum (the syphilis bacterium), Mycobacterium tuberculosis, Vibrio cholerae, Bacillus anthracis (anthrax), and many others.  He and his research team developed a eukaryotic gene finder for Plasmodium falciparum, the malaria parasite, and later adapted it for the human genome, the model plant Arabidopsis thaliana, Oryza sativa (rice), Cryptococcus neoformans, Brugia malayi, and other species. 

Salzberg's lab has a major focus on next-generation sequence alignment and on large-scale genome assembly. They have assembled hundreds of genomes, large and small, and developed a variety of genome assembly algorithms, including the open-source AMOS assembly package. In recent years Salzberg and his students have introduced several pioneering, highly efficient systems for alignment of next-generation sequencing reads, including the Bowtie, Tophat, and Cufflinks systems, which are now used by thousands of labs around the world. All of the group's software is free and open source, and their systems have been downloaded hundreds of thousands of times.  In addition to his software systems, Salzberg has contributed analyses to many genome sequencing projects, including the human genome, multiple plant and animal genomes, and many bacteria. He was a co-founder of the Influenza Genome Sequencing Project, the first large-scale genomics study of human and avian influenza viruses.

Dr. Salzberg has authored or co-authored over 225 publications in leading scientific journals, and his h-index is 112. He is a Fellow of the American Association for the Advancement of Science (AAAS), a Fellow of the International Society for Computational Biology (ISCB), and a former member of the Board of Scientific Counselors of the National Center for Biotechnology Information at NIH. He was the 2013 winner of the Benjamin Franklin Award for Open Access in the Life Sciences, and the 2013 winner of the Robert G. Balles Prize in Critical Thinking for his Forbes science column. In 2001 and again in 2014 he was listed as a Highly Cited Researcher by Thomson Reuters, a compilation of the 1% most-cited researchers in the world. He currently serves on the Editorial Boards of the journals Genome Biology, PeerJ Computer Science, BMC Biology, Journal of Computational Biology, PLoS ONE, BMC Genomics, BMC Bioinformatics, and Biology Direct, and he is a member of the Faculty of 1000. He co-chaired the Third (1999) through the Eighth (2005) Conferences on Computational Genomics, the 2007 and 2009 International Conferences on Microbial Genomics, and the 2009 Workshop on Algorithms in Bioinformatics.