2017 Core Coins Program
High-throughput sequencing makes it possible to unlock the molecular
and genetic bases of diseases, but analyzing the large sequence data
sets requires computational resources and expertise that may not be
available to all investigators. In response to the growing demand for
sequence analysis, the School of Medicine is offering Core ‘coins’
awards through the
Computational Biology Consulting Core (CBCC). The
awards will provide scientists with leading-edge bioinformatics analysis
of RNA sequencing (RNA-seq) or 16S rRNA metagenomics data sets, to be performed
at the CBCC. Each award will cover or help defray the cost of analyses,
up to a maximum of $5,000. Any additional analysis costs will be the
responsibility of the investigator (estimated project costs by data set
size are diagramed below). Applications are due by September 30, 2017,
and successful proposals will be announced by October 15, 2017.
NOTE: Winners were announced, and the Core Coins competition for 2017 is now closed.
Applications must be very brief, consisting of: i) a one-page project
description, ii) a brief justification for the scope and need for the
project and/or how the project responds to this RFA, and iii) the number
of, and a brief description of the data sets. Priority will be given to
proposals from junior investigators, pilot projects to provide support
for grant applications, and analyses of new data, and will be based on
agreement from investigators to recognize the Core ‘coins’ program and
the CBCC in publications generated as a result of this funding. All data
for analyses must be available by the end of the FY2018. Please submit
your proposal through the CBCC iLab portal or email it to Liliana Florea
(florea@jhu.edu), Associate Professor, Faculty Manager, Computational
Biology Consulting Core.
Estimated costs by size of data set.
| RNA-seq samples | Price estimate | Price per sample |
|---|---|---|
| (40-100 M reads/sample†) | ($) | ($) |
| | | |
| 2 | 1,450 | 725 |
| 3 | 1,850 | 617 |
| 4 | 2,300 | 575 |
| 5 | 2,750 | 550 |
| 6 | 3,150 | 525 |
| 7 | 3,575 | 510 |
| 8 | 4,050 | 506 |
| 9 | 4,475 | 497 |
| 10 | 4,950 | 495 |
| 20 | 8,800 | 440 |
| 40 | 15,525 | 388 |
| 60 | 20,700 | 345 |
| 80 | 24,400 | 305 |
| 100 | 27,300 | 273 |
| 150 | 34,500 | 230 |
| 200 | 40,000 | 200 |
| >200 | Var. | 200 |
| 16S rRNA samples | Estimated price ($) | Price per sample ($) |
|---|---|---|
| | | |
| <20 | 2,000 | Var. |
| 40 | 3,500 | 88 |
| 60 | 5,000 | 83 |
| 80 | 6,500 | 81 |
| 100 | 8,000 | 80 |
| 150 | 11,000 | 73 |
| 200 | 14,000 | 70 |
| 250 | 16,500 | 66 |
| 300 | 19,000 | 63 |
| 350 | 21,500 | 61 |
