The Center for Computational Biology
A joint research center in the McKusick-Nathans Institute of Genetic Medicine, spanning the School of Medicine, the Whiting School of Engineering, the Bloomberg School of Public Health, and the Krieger School of Arts & Sciences
- April 13, 2017. A group of CCB scientists publish recount2 in Nature Biotechnology. recount2 provides processed and summarized expression data for over 70,000 human RNA-seq ...(read more)
- December 30, 2016. Abhi Nellore, Kasper Hansen, Ben Langmead, Jeff Leek and co-authors publish a study in Genome Biology examining splicing diversity and unannotated splicing in humans. It is also discussed ...(read more)
- December 15, 2016. Daehwan Kim, Li Song, and Florian Breitwieser publish Centrifuge, a new, highly efficient metagenomics classifer. See the paper at Genome Research here.
- Oct. 26-29, 2016. The 2016 Biological Data Science conference at Cold Spring Harbor Lab is co-chaired by CCB members Jeff Leek (Biostatistics) and Michael Schatz (Computer Science).
- August 11, 2016. Mihaela Pertea and colleagues publish a new protocol describing how to use StringTie, HISAT, and Ballgown to analyze RNA sequencing experiments, including alignment of raw reads, assembly and quanitification of transcripts, and ...(read more)
The Center for Computational Biology (CCB) is a multidisciplinary center dedicated to research on genomics, genetics, DNA sequencing technology, and computational methods for DNA and RNA sequence analysis. CCB brings together scientists and engineers from many fields, including computer science, biostatistics, biomedical engineering, genomics, genetics, molecular biology, physics, and mathematics, all of whom share a common interest in gaining a better understanding of how genes and genomes affect biological functions. We develop and apply technology that uses sequence data to study a wide range of questions, including how genes cause disease, how genes change in response to different conditions within the cell, and how genomes evolve.
In addition to its research program, CCB provides bioinformatics expertise to departments and centers throughout the Schools of Medicine and Public Health, through a consulting group trained in the latest computational methods for sequence analysis. More about CCB ...»